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NanoRelease Information Catalog

As part of the NanoRelease project we will be collecting and collating data, methods, guidance, standards, and links to efforts that provide this kind of information relevant to the materials and methods being considered for review and development. The current catalog is organized as follows:

PROJECT LINKS

The following projects consider aspects of measurement of release of nanomaterials:

 

·         Aging, Nano, & Troph: This is a multi-stage project that endeavors to identify and quantify residues from the degradation of products containing nanomaterial. The group plans to utilize standardized accelerated aging protocols on a select panel of nanoparticle/carrier systems, including titania coating on self-cleaning glasses, cerium oxide in exterior paints, titania/zinc oxide in sunscreen, and titania in cement.
·         California—Department of Toxic Substances Control (DTSC): Through data calls on nanomaterials, DTSC is seeking information on uses and potential for release along the value chain for selected nanomaterials.
·         ENPRA: This major new European Framework 7 project aims to develop and implement a novel integrated approach for engineered nanoparticle risk assessment.
·         HINAMOX: The work of the HINAMOX consortium focuses on metal and metal oxide nanoparticles as potentially dangerous to biological organisms.
·         INNO.CNT
o    CarboSafe: “The fundament of the project work is the development of well-grounded measuring technologies that are able to clearly detect the release rates of nano­particles throughout the lifecycle of products based on CNT.” (from project brochure)
o    CarboLifeCycle: “The core tasks of the project, in addition to further eco-toxicological considerations, in­clude the development of personal measuring technology worn on the body, further refinement of measuring strategies, and measurements of potential exposure during the manufacture, processing, use, and the end of life of CNT and CNT-based products.” (from project brochure)
·         MARINA Project
·         Nanex: The aim of the NANEX project is to develop a catalog of occupational, consumer and environmental release exposure scenarios for engineered nanomaterials (ENMs), taking account of the entire life-cycle of these materials. The project review available exposure information, focusing on three very relevant ENMs: (1) high aspect ratio nanomaterials (e.g., carbon nanotubes); (2) mass-produced nanomaterials (e.g., n-ZnO, n-TiO2, carbon black); and (3) specialized nanomaterials that are currently only produced on a small scale (e.g., n-Ag). The exposure information will include both quantitative (measurement results) and qualitative contextual exposure information (risk management measures).
·         NanoDevice: The goal of the Nanodevice project is to develop innovative concepts and reliable methods for characterizing engineered nanoparticles (ENP) in workplace air with portable and easy-to-use devices. In addition, the project endeavors to: (1) identify relevant physico-chemical properties and metrics of airborne ENP; (2) explore the association between physico-chemical and toxicological properties; (3) analyze industrial processes as a source of airborne ENP; (4) develop methods for calibration and testing of the novel devices in real and simulated exposure situations; and (5) disseminate the results through guidance,
standards and education, to promote safe ENP production and handling.
·         NanoGem: This is a project combining several stakeholders interested in evaluating industrially relevant nanomaterials contained in processed products, with special attention to the uptake and distribution of nanoparticles in the human body as a function of size, structure, and surface properties. Issues of safety at work and product safety during manufacturing, processing, application, and disposal will be approached by means of newly developed portable measuring instruments.
·         Nanolyse: This project is a consortium composed of 10 universities and research centers from Europe and Canada that endeavors to develop analytical methods for the detection and characterization of engineered nanoparticles in foods.
·          NANOPOLYTOX: The objective of this project is to monitor the physio-chemical properties of three nanomaterials (carbon nanotubes, nanoclays, and metal oxide nanoparticles) embedded in polymeric films during the entire life cycle (synthesis, processing, aging, recycling/disposal). The theoretical analysis of the data collected will lead to the development of predictive models to assess the biological and environmental fate of these nanomaterials.
          
·         NanoSustain: The main objective of the NanoSustain project is to develop innovative solutions for the sustainable design, use, recycling and final disposal nanotechnology based products. This will be based on a comprehensive hazard characterization and impact assessment of four environmentally and economically relevant products, including: (1) nanocellulose based products, (2) CNT based products, (3) n-ZnO based composites, and (4) n-TiO2 based products.
·         National Institute of Standards and Technology (NIST)—Nanotechnology Portal: NIST is developing standard reference materials and methods for measuring nanomaterial release from specific materials and at different stages along the life cycle of uses (for example, incineration of materials containing manufactured nanomaterials)
·         National Research Centre for the Working Environment—Project on Nanoparticles in the Paint and Lacquer Industry. Exposure and Toxic Properties: The goals of this project are to identify and characterize the risks associated with exposure to nanoparticles from paints or in dust from paints containing nanoparticles. This effort will progress with four concurrent sub-projects: (1) assessment of the exposure risks associated with dust generated from nanoparticle-containing paints, (2) characterization of physio-chemical properties of nanoparticles and dust, (3) characterization of toxic properties of nanoparticles and dust generated from nanoparticle-containing paints, and (4) development of risk assessment models for nanoparticles used or expected to be used in the paint and lacquer industries.
·        NEPHH: This project aims to identify and rate importanty forms of nanotechnology-related enviormental pollution and health hazards that could result from activities involved in nanostructures throughout their life cycle, and to sugest means that might reduce or eliminate these impacts.
o    WPMN Steering Group 3 is developing methods and data for the characterization of manufactured nanomaterials.
o    WPMN Steering Group 8 is collecting and developing information on exposure to manufactured nanomaterials, including methods for measuring exposure.
·         Rice University, Center for Biological and Environmental Nanotechnology— Measuring Nanoparticles in Biological and Environmental Settings: The Center has been supporting the development of analytical tools and methods to permit the characterization of nanoparticles without destroying the biological interface. Current tools (e.g., SEM, X-ray diffraction) used to characterize nanoparticles do so at the expense of the biological and environmental context. In addition to characterization, researchers are developing methods to track nanoparticle motion in environmental and biological media. The Center intends to further develop these tools to improve nanomaterial engineering outcomes.
·         TRACER Project—Toxicology and Health Risk Assessment of Carbon Nanomaterials: The TRACER project (2006-2009) aimed to assess the biocompatibility of polyether-ether ketone and polyurethane composite with carbon nanomaterials along the value chain. Comprehensive physicochemical characterization of the materials and simulation tools were adapted for use with carbon nanomaterials to facilitate prediction of the dose-response correlation. Together, the results are included in the evaluation of size-resolved determinations of the number of particles released along the value chain, and are used as a basis for handling recommendations.
 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

​​NANORELEASE PROJECT

Phase 1: Nanomaterial Selection (completed)
Phase 2: Methods Evaluation (in progress)
Phase 3: Interlaboratory Studies (late 2012)
RESOURCES
 
CONTACT US
Richard Canady, PhD, DABT
Director, RSIA
NanoRelease@ilsi.org
 
WHAT IS RSIA?
 
This project was undertaken with the financial support of the Government of Canada through the Federal Department of the Environment.

Ce project a été réalisé avec l'appui financier du Gouvernement du Canada agissant par l'entremise du ministère fédéral de l'Environnement.​​​

SHARE YOUR COMMENTS

You can provide suggestions for what should be considered by e-mailing information to NanoRelease@ilsi.org. Please let us know if you would like us to attribute your suggestion to you.